| New benzophenone and quercetin galloyl glycosides from Psidium guajava L. | |
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MedLine Citation:
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PMID: 20354804 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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New benzophenone and flavonol galloyl glycosides were isolated from an 80% MeOH extract of Psidium guajava L. (Myrtaceae) together with five known quercetin glycosides. The structures of the novel glycosides were elucidated to be 2,4,6-trihydroxybenzophenone 4-O-(6''-O-galloyl)-beta-D: -glucopyranoside (1, guavinoside A), 2,4,6-trihydroxy-3,5-dimethylbenzophenone 4-O-(6''-O-galloyl)-beta-D: -glucopyranoside (2, guavinoside B), and quercetin 3-O-(5''-O-galloyl)-alpha-L: -arabinofuranoside (3, guavinoside C) by NMR, MS, UV, and IR spectroscopies. Isolated phenolic glycosides showed significant inhibitory activities against histamine release from rat peritoneal mast cells, and nitric oxide production from a murine macrophage-like cell line, RAW 264.7. |
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Authors:
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Keiichi Matsuzaki; Rie Ishii; Kaori Kobiyama; Susumu Kitanaka |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-03-31 |
Journal Detail:
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Title: Journal of natural medicines Volume: 64 ISSN: 1861-0293 ISO Abbreviation: J Nat Med Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-05-28 Completed Date: 2010-08-30 Revised Date: 2010-09-30 |
Medline Journal Info:
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Nlm Unique ID: 101518405 Medline TA: J Nat Med Country: Japan |
Other Details:
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Languages: eng Pagination: 252-6 Citation Subset: IM |
Affiliation:
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Research Unit of Pharmacognosy, College of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba 274-8555, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anti-Inflammatory Agents / chemistry, pharmacology Benzophenones / chemistry* Cell Line Glycosides / chemistry*, pharmacology Histamine / metabolism Macrophages / cytology, drug effects, metabolism Magnetic Resonance Spectroscopy Mast Cells / cytology, drug effects, metabolism Mice Molecular Structure Nitric Oxide / metabolism Plant Leaves / chemistry Psidium / chemistry* Quercetin / chemistry* Rats |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 0/Benzophenones; 0/Glycosides; 10102-43-9/Nitric Oxide; 117-39-5/Quercetin; 119-61-9/benzophenone; 51-45-6/Histamine |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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