| New balloon-thermography catheter for in vivo temperature measurements in human coronary atherosclerotic plaques: a novel approach for thermography? | |
| | |
MedLine Citation:
|
PMID: 12594700 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Although ex vivo studies showed marked thermal heterogeneity in atheromatic plaques, in in vivo human studies trivial temperature variations are recorded due to the cooling effect of blood flow. We investigated a new balloon-thermogaphy catheter for temperature measurements during coronary flow interruption. A thermistor probe is positioned at the distal segment of the catheter. At the opposite site of the thermistor, a balloon is placed. By inflation of the balloon, coronary flow is interrupted. Ten patients with effort angina were studied. Coronary flow velocity was continuously recorded. Temperature was recorded at the proximal vessel wall and at the lesion before, during, and after complete interruption of blood flow by inflation of the balloon. DeltaTp was assigned as the difference between the background temperature and the maximal temperature during and after balloon inflation. DeltaTl was assigned as the difference between the atherosclerotic plaque and the proximal vessel wall. The procedure was not complicated. DeltaTp during and after balloon inflation was 0.01 +/- 0.01 degrees C and -0.003 +/- -0.01 degrees C (P < 0.001), respectively. DeltaTl was 0.07 +/- 0.04 degrees C at baseline, 0.17 +/- 0.06 degrees C (59.3% +/- 11.8% increase) during, and 0.07 +/- 0.05 degrees C after flow interruption (P < 0.001). DeltaTl was greater than DeltaTp during and after impairment of flow (P < 0.001). In vivo atherosclerotic plaque temperature recording seems to be feasible with this new balloon-thermography catheter. This device may introduce a new approach for the detection of thermal heterogeneity in plaques by addressing the issue of cooling effect of blood flow. |
| | |
Authors:
|
Christodoulos Stefanadis; Konstantinos Toutouzas; Manolis Vavuranakis; Eleftherios Tsiamis; Sophia Vaina; Pavlos Toutouzas |
Publication Detail:
|
Type: Evaluation Studies; Journal Article |
Journal Detail:
|
Title: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions Volume: 58 ISSN: 1522-1946 ISO Abbreviation: Catheter Cardiovasc Interv Publication Date: 2003 Mar |
Date Detail:
|
Created Date: 2003-02-20 Completed Date: 2003-06-10 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 100884139 Medline TA: Catheter Cardiovasc Interv Country: United States |
Other Details:
|
Languages: eng Pagination: 344-50 Citation Subset: IM |
Copyright Information:
|
Copyright 2003 Wiley-Liss, Inc. |
Affiliation:
|
Department of Cardiology, Hippokration Hospital, Athens Medical School, Athens, Greece. cstefan@cc.uoa.gr |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Angina Pectoris / etiology, physiopathology*, radiography Balloon Dilatation / instrumentation* Blood Flow Velocity / physiology Body Temperature / physiology* Coronary Angiography Coronary Artery Disease / complications, physiopathology*, radiography Coronary Circulation / physiology Equipment Design Feasibility Studies Female Humans Male Middle Aged Reproducibility of Results Thermography / instrumentation* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Oral acetylcysteine does not protect renal function from moderate to high doses of intravenous radio...
Next Document: In-hospital outcomes of contemporary percutaneous coronary interventions in the very elderly.