Document Detail


New aspects for the role of physical training in the management of patients with chronic heart failure.
MedLine Citation:
PMID:  12821212     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recent experimental and clinical data have shown that physical training is an important therapeutic intervention in the management of patients with chronic heart failure (CHF), improving central hemodynamics and attenuating peripheral abnormalities (endothelial dysfunction and skeletal myopathy) characterizing the progression of the syndrome. Additionally, physical training seems to beneficially modulate peripheral immune responses of CHF expressed by elevated circulating proinflammatory cytokines, soluble cellular adhesion molecules and soluble apoptosis signaling molecules, resulting in improvement in exercise capacity of CHF patients. This article summarizes current knowledge about the beneficial role of physical training in CHF, as well as about traditional and novel mechanisms contributing to the physical training-induced improvement in clinical performance of CHF patients.
Authors:
Stamatis Adamopoulos; John T Parissis; Dimitrios Th Kremastinos
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  International journal of cardiology     Volume:  90     ISSN:  0167-5273     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2003 Jul 
Date Detail:
Created Date:  2003-06-24     Completed Date:  2003-11-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  1-14     Citation Subset:  IM    
Affiliation:
Second Department of Cardiovascular Medicine, Onassis Cardiac Surgery Center, Athens, Greece. sadamo@bigfoot.com
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MeSH Terms
Descriptor/Qualifier:
Chronic Disease
Exercise Therapy*
Exercise Tolerance / physiology
Heart Failure / physiopathology*,  therapy*
Humans

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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