Document Detail


New aspects of laser microdissection in research and routine.
MedLine Citation:
PMID:  15750030     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Laser microdissection has opened a window to new technologies. The scientific fields of genomics, transcriptomics, and proteomics need pure samples for rendering reliable results. Homogeneous sample preparation is a prerequisite for modern molecular analyses, both qualitative and quantitative. Laser microdissection and pressure catapulting (LMPC) is a tool for isolating specific cells from complex tissues in a non-contact and contamination-free manner. Because LMPC technology is an optimal method for obtaining fast and reliable access to single cells, the possibility of automatic isolation of single fetal cells has the promise of being a big step forward in developing protocols for non-invasive prenatal diagnosis.
Authors:
Renate Burgemeister
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society     Volume:  53     ISSN:  0022-1554     ISO Abbreviation:  J. Histochem. Cytochem.     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-03-07     Completed Date:  2005-04-22     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9815334     Medline TA:  J Histochem Cytochem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  409-12     Citation Subset:  IM    
Affiliation:
P.A.L.M. Microlaser Technologies AG, Am Neuland 9+12, 82347 Bernried, Germany. Renate.Burgemeister@palm-microlaser.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Autoanalysis
Cell Separation / methods*
Cytogenetic Analysis / methods
Female
Fetus / cytology
Forensic Medicine
Humans
Lasers*
Microdissection / methods*
Pregnancy
Prenatal Diagnosis / methods
RNA / isolation & purification
Specimen Handling / methods*
Chemical
Reg. No./Substance:
63231-63-0/RNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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