Document Detail


New aspects in lipidology and atherosclerosis.
MedLine Citation:
PMID:  7750049     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recent advances in lipidology and metabolic aspects of atherosclerosis allow detailed coronary artery disease (CAD) risk assessment that is of clinical relevance. Genetic dyslipidemias can be identified in over 75% of CAD patients and include the atherosclerosis susceptibility trait (low density lipoprotein [LDL] pattern B), hyperapobetalipoproteinemia, lipoprotein (a), apo E isoforms, and lipoprotein susceptibility to oxidative damage. The inherited amino acid disorder homocysteinemia is present in approximately 20% of CAD patients and is easily treated. Recent studies have highlighted significant differences in response to diet and drug therapy that can be predicted based on the presence or absence of these traits.
Authors:
H R Superko
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The Canadian journal of cardiology     Volume:  11 Suppl C     ISSN:  0828-282X     ISO Abbreviation:  Can J Cardiol     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-06-19     Completed Date:  1995-06-19     Revised Date:  2008-04-09    
Medline Journal Info:
Nlm Unique ID:  8510280     Medline TA:  Can J Cardiol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  4C-8C     Citation Subset:  IM    
Affiliation:
Lawrence Berkeley Laboratory, University of California, Berkeley Lipid Institute, Sequoia Hospital, Redwood City 94062-2799, USA.
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MeSH Terms
Descriptor/Qualifier:
Antilipemic Agents / therapeutic use
Apolipoproteins / blood
Cholesterol, LDL / blood
Coronary Artery Disease / blood*,  etiology,  genetics,  therapy
Disease Susceptibility
Female
Humans
Hyperlipoproteinemias / complications,  genetics*,  therapy
Lipoprotein(a) / blood
Lipoproteins / blood*
Male
Risk Factors
Chemical
Reg. No./Substance:
0/Antilipemic Agents; 0/Apolipoproteins; 0/Cholesterol, LDL; 0/Lipoprotein(a); 0/Lipoproteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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