| New aspects in the clinical spectrum of neonatal lupus. | |
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MedLine Citation:
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PMID: 22105871 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Neonatal lupus erythematosus (NLE) is a rare, passively acquired autoimmune disease, caused by maternal autoantibodies. Characteristic clinical features of NLE are transient rash and congenital heart block (CHB), but also hematological abnormalities and hepatobiliary dysfunction may occur. Complications to the transient dermatitis are rarely described. We describe two patients with NLE and cutaneous manifestations. Both patients had involvement of the sun-protected genital skin and soles. New manifestations of NLE were gastrointestinal bleeding in one patient despite normal coagulation parameters, but with mucosal telangiectatic lesions found on sigmoidoscopy. In addition, one patient developed painful atrophy after plantar dermatitis on follow-up with need of orthopedic footwear. CHB was not found. In conclusion, NLE may be complicated with sigmoidal telangiectasia with rectal bleeding and painful plantar atrophy. |
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Authors:
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Rasa Laurinaviciene; Henrik Thybo Christesen; Anette Bygum |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-22 |
Journal Detail:
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Title: European journal of pediatrics Volume: - ISSN: 1432-1076 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7603873 Medline TA: Eur J Pediatr Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Dermatology and Allergy Centre, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense, Denmark, rlaur@hotmail.dk. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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