Document Detail

New aspects on the assessment of left ventricular dyssynchrony by tissue Doppler echocardiography: comparison of myocardial velocity vs. displacement curves.
MedLine Citation:
PMID:  19655270     Owner:  NLM     Status:  MEDLINE    
The purpose of this study is to assess the incremental value of tissue Doppler (TDI) derived displacement curves (TDint) compared to TDI velocity curves (TDvel) for the evaluation of left ventricular (LV) dyssynchrony (LVD). About 25 patients (pts.) with systolic heart failure were studied by TDvel and TDint. Four TDI sample volumes were placed at the basal and four at the mid ventricular myocardium, utilising two imaging planes. LV dyssynchrony (LVD) was defined as an interregional delay of >40 ms corrected for heart rate. 10 pts. had synchronous contraction, 15 pts. LVD as defined by two experts (EC). To determine diagnostic accuracy and intra-observer variability two identical sets of 100 documents (25 pts. x two imaging planes x two modalities) were produced and presented in random order to one trained (TR) and two untrained (UR) readers. The TR more frequently classified documents as unreadable (7.5 vs. 3.5%, P < 0.05) but more often as correct, i.e., consistent with EC (72.0 vs. 57.8%, P < 0.001). 8.7% of the documents were classified as unreadable using TDvel, 1.0% when applying TDint (P < 0.001). The mean value of correct classification of all 3 readers was 54.3% (TDvel only), 70.7% (TDint only), and 77.7% (combining both modalities), (P < 0.001). The kappa value for TR and TDint was 0.68, for TDvel 0.29. For UR, kappa did not differ (TDint: 0.58; TDvel 0.51). TDint is superior to TDvel in accuracy, reproducibility, and applicability for skilled and unskilled investigators when evaluating LVD by TDI. The combined application of TDint and TDvel is optimal.
N Bogunovic; D Hering; F van Buuren; D Welge; B Lamp; D Horstkotte; L Faber
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-08-05
Journal Detail:
Title:  The international journal of cardiovascular imaging     Volume:  25     ISSN:  1875-8312     ISO Abbreviation:  -     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-08-20     Completed Date:  2009-10-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100969716     Medline TA:  Int J Cardiovasc Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  699-704     Citation Subset:  IM    
Department of Cardiology, Heart and Diabetes Center North Rhine-Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.
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MeSH Terms
Cardiac Pacing, Artificial
Clinical Competence
Echocardiography, Doppler, Color*
Heart Failure, Systolic / physiopathology,  therapy,  ultrasonography*
Heart Rate
Myocardial Contraction*
Observer Variation
Patient Selection
Predictive Value of Tests
Reproducibility of Results
Time Factors
Ventricular Dysfunction, Left / physiopathology,  therapy,  ultrasonography*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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