Document Detail


New approaches to therapy with omega-3 fatty acids.
MedLine Citation:
PMID:  18366989     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
With greater focus on chronic disease prevention, renewed attention has been directed toward understanding the pathophysiology of various medical conditions and the development of newer medical treatments to prevent and treat complications. There has been immense interest in evaluating societal lifestyles, cultural attitudes toward health, and dietary influences on health conditions. The omega-3 fatty acids have become a focus of interest, and recent research and trial evidence have highlighted their effects, including potential clinical advantages. Despite this progress, the precise mechanisms through which omega-3 fatty acids act remain poorly understood. These agents are now recommended as secondary prevention after acute myocardial infarction, and ongoing large clinical trials should provide insight into the use of omega-3 fatty acids in heart failure and the primary prevention of cardiovascular disease.
Authors:
Puneet Kakar; Timothy Watson; Gregory Y H Lip
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current atherosclerosis reports     Volume:  10     ISSN:  1534-6242     ISO Abbreviation:  Curr Atheroscler Rep     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-03-27     Completed Date:  2008-05-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100897685     Medline TA:  Curr Atheroscler Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  79-87     Citation Subset:  IM    
Affiliation:
University Department of Medicine, City Hospital, Birmingham B18 7QH, UK. g.y.h.lip@bham.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Arrhythmias, Cardiac / physiopathology
Blood Platelets / physiology
Blood Pressure / drug effects
Cardiovascular Diseases / mortality,  physiopathology,  prevention & control
Cell Adhesion Molecules / physiology
Endothelium, Vascular / drug effects,  physiology
Fatty Acids, Omega-3 / pharmacology*,  therapeutic use*
Fibrinolysis / drug effects
Fish Oils / therapeutic use
Humans
Myocardial Infarction / prevention & control
Plant Oils / therapeutic use
Randomized Controlled Trials as Topic
Stroke / prevention & control
Survival Analysis
Chemical
Reg. No./Substance:
0/Cell Adhesion Molecules; 0/Fatty Acids, Omega-3; 0/Fish Oils; 0/Plant Oils

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