| New approaches to pathogenesis of malaria in pregnancy. | |
| | |
MedLine Citation:
|
PMID: 17958924 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Malaria infection during pregnancy is associated with poor maternal and foetal outcomes including low birth weight. In malaria-endemic areas, low birth weight is primarily a consequence of foetal growth restriction. Little is known on the pathogenesis of foetal growth restriction and our understanding of the relationship between epidemiological observations and the pathogenesis or consequences of disease is incomplete. In this review, we describe these gaps in our knowledge and also try to identify goals for future research into malaria in pregnancy. Foetal growth restriction results from a complex four-dimensional interaction between the foetus, the mother and the malaria parasite over gestation, and research into its pathogenesis may be advanced by combining longitudinal studies with techniques and approaches new to the field of malaria in pregnancy. Such approaches would greatly increase our knowledge on the pathogenesis of this disease and may provide new avenues for intervention strategies. |
| | |
Authors:
|
S J Rogerson; P Boeuf |
Related Documents
:
|
23126244 - Medical versus surgical termination of pregnancy in primigravid women-is the next deliv... 23129074 - Differing attitudes toward fetal care by pediatric and maternal-fetal medicine speciali... 23389374 - Irinotecan during pregnancy in metastatic colon cancer. 21180984 - Assessment of protein intake during pregnancy using a food frequency questionnaire and ... 19322574 - Predicting fetal asphyxia in intrahepatic cholestasis of pregnancy. 16725494 - Lactate dehydrogenase isoenzyme patterns as a method of pregnancy detection in cattle. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
|
Title: Parasitology Volume: 134 ISSN: 0031-1820 ISO Abbreviation: Parasitology Publication Date: 2007 |
Date Detail:
|
Created Date: 2007-10-25 Completed Date: 2008-07-01 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0401121 Medline TA: Parasitology Country: England |
Other Details:
|
Languages: eng Pagination: 1883-93 Citation Subset: IM |
Affiliation:
|
Department of Medicine (RMH/WH), Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia. sroger@unimelb.edu.au |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Female Humans Malaria / complications*, physiopathology*, prevention & control Pregnancy Pregnancy Complications, Parasitic / drug therapy, pathology*, physiopathology* |
| Grant Support | |
ID/Acronym/Agency:
|
//Wellcome Trust |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Plasmodium in the placenta: parasites, parity, protection, prevention and possibly preeclampsia.
Next Document: Cellular and molecular physiopathology of congenital toxoplasmosis: the dual role of IFN-gamma.