| New approaches to hepatocellular carcinoma and concomitant esophageal varices prolong survival. | |
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MedLine Citation:
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PMID: 2174828 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A retrospective study was done on 226 patients with hepatocellular carcinoma and coexisting esophageal varices treated at our institute between 1974 and 1988. The patients were divided into two groups: Group A containing patients treated between 1974 and 1982 (n = 92), and Group B comprising those treated between 1983 and 1988 (n = 134). Surgical treatments were applied to 64 patients (69.6%) and 37 patients (27.6%) in groups A and B, respectively (p less than 0.001). Ninety out of 134 patients (67.2%) in group B were prescribed regional chemotherapy. Forty-nine patients (53.3%) in group A, and 96 (71.6%) in group B had esophageal varices that were about to rupture as indicated endoscopically. Nineteen patients (38.8%) in group A, and 10 (10.4%) in group B were treated surgically (p less than 0.005). The varices in 76 out of 96 patients (79.2%) in group B were treated by endoscopic sclerotherapy. Survival rates during the first 5 years in groups A and B were 28% and 65%, 16% and 43%, 5% and 27%, 4% and 18%, and 4% and 6%, respectively. It would appear that appropriate conservative treatment of the poor surgical candidates will, in general, lead to good clinical results. |
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Authors:
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T Matsumata; T Kanematsu; K Shirabe; T Sonoda; S Kitano; K Sugimachi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Hepato-gastroenterology Volume: 37 ISSN: 0172-6390 ISO Abbreviation: Hepatogastroenterology Publication Date: 1990 Oct |
Date Detail:
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Created Date: 1991-01-24 Completed Date: 1991-01-24 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8007849 Medline TA: Hepatogastroenterology Country: GERMANY |
Other Details:
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Languages: eng Pagination: 489-93 Citation Subset: IM |
Affiliation:
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Second Department of Surgery, Kyushu University, Faculty of Medicine, Fukuoka, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Carcinoma, Hepatocellular / complications, mortality, therapy* Esophageal and Gastric Varices / complications, therapy* Female Humans Liver Neoplasms / complications, mortality, therapy* Male Middle Aged |
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