Document Detail


New approaches to drug selection and serial drug testing.
MedLine Citation:
PMID:  6207209     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sudden cardiac death is a major problem in the United States. Our goal is to identify high-risk patients and to be able to target antiarrhythmic therapy to this population. Ambulatory electrocardiography, exercise tolerance testing, and programmed electrical stimulation studies may aid in the identification of patients at risk for sudden cardiac death and the selection of antiarrhythmic therapy. Each technique has its advantages, disadvantages, and limitations. These considerations must be taken into account if the procedure is to be optimally employed. We are in a period of rapid development of new antiarrhythmic agents. It is essential to fully understand the techniques employed to evaluate antiarrhythmic therapy.
Authors:
J C Somberg
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical pharmacology     Volume:  24     ISSN:  0091-2700     ISO Abbreviation:  J Clin Pharmacol     Publication Date:  1984 Jul 
Date Detail:
Created Date:  1984-11-19     Completed Date:  1984-11-19     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0366372     Medline TA:  J Clin Pharmacol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  320-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Anti-Arrhythmia Agents / adverse effects,  therapeutic use*
Arrhythmias, Cardiac / drug therapy,  etiology,  physiopathology*
Cardiac Complexes, Premature / mortality
Coronary Disease / physiopathology
Death, Sudden / prevention & control
Electric Stimulation
Electrocardiography
Exercise Test
Humans
Monitoring, Physiologic
Risk
Tachycardia / physiopathology
Chemical
Reg. No./Substance:
0/Anti-Arrhythmia Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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