| New approaches to the diagnosis of preterm labor. | |
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MedLine Citation:
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PMID: 9914626 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is a pressing need to develop accurate methods of diagnosing true preterm labor because of the availability of potent tocolytic drugs and the known beneficial effects of antenatal glucocorticoid administration on neonatal outcomes of premature infants. Maternal plasma corticotropin-releasing hormone concentrations are elevated in women with threatened preterm labor between 28 and 36 weeks' gestation who give birth within 24 hours. In addition, the ratio of cortisol to corticosteroid binding capacity is elevated in the plasma of women who give birth within 24 hours. These data support the design and conduct of a prospective clinical trial to determine the positive and negative predictive values of these markers for preterm birth in women with symptoms. |
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Authors:
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A D Bocking; J R Challis; C Korebrits |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 180 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1999 Jan |
Date Detail:
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Created Date: 1999-02-22 Completed Date: 1999-02-22 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: S247-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynaecology, University of Western Ontario, Lawson Research Institute, St. Joseph's Health Centre, London, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Cortex Hormones
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metabolism Carrier Proteins / blood Corticotropin-Releasing Hormone / blood Delivery, Obstetric Female Humans Hydrocortisone / blood Obstetric Labor, Premature / blood, diagnosis* Obstetrics / methods* Pregnancy Pregnancy Trimester, Third / blood Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Carrier Proteins; 50-23-7/Hydrocortisone; 9015-71-8/Corticotropin-Releasing Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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