| New approaches for designing and evaluating food fortification programs. | |
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MedLine Citation:
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PMID: 16549476 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Historically, food fortification programs were often undertaken with little attention to issues such as micronutrient bioavailability, optimal levels of addition, or efficacy or to monitoring impact on nutritional status, health, and human function. Several developments in recent years have enabled substantial progress to be made in the design and evaluation of fortification programs. The methodology for estimating the prevalence of inadequate nutrient intakes in a population and tolerable upper intake levels has been established and can be used as the basis for estimating desirable amounts of nutrient addition. More attention is being paid to assessing the bioavailability of nutrients (especially minerals) using stable and radioactive isotopes, and bioavailability of iron compounds can be estimated from changes in total body iron calculated from the ratio of transferrin receptors to serum ferritin. Procedures for quality control of the fortification process have been established. New approaches to monitoring the impact of fortification over time include assessment of liver retinol stores using retinol isotope dilution. In summary, the design and evaluation of food fortification programs now requires a series of formative research procedures on the part of nutritionists, which were not often expected or conducted in the past. |
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Authors:
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Lindsay H Allen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of nutrition Volume: 136 ISSN: 0022-3166 ISO Abbreviation: J. Nutr. Publication Date: 2006 Apr |
Date Detail:
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Created Date: 2006-03-21 Completed Date: 2006-05-03 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0404243 Medline TA: J Nutr Country: United States |
Other Details:
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Languages: eng Pagination: 1055-8 Citation Subset: IM |
Affiliation:
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U.S. Department of Agriculture, ARS Western Human Nutrition Research Center, University of California, Davis, CA 95616, USA. lhallen@ucdavis.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biological Availability Developing Countries Food, Fortified* Humans Iron / pharmacokinetics Liver / chemistry Minerals / pharmacokinetics Nutritional Physiological Phenomena* Quality Control Research Vitamin A / analysis |
| Chemical | |
Reg. No./Substance:
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0/Minerals; 11103-57-4/Vitamin A; 7439-89-6/Iron |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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