| New agents for the treatment of gout and hyperuricemia: febuxostat, puricase, and beyond. | |
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MedLine Citation:
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PMID: 20425022 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The rising prevalence of gout has led the pharmaceutical industry to rediscover what it had considered a forgotten disease. In April 2009, the Food and Drug Administration (FDA) approved febuxostat (Takeda Pharmaceuticals; Deerfield, IL), the first new urate-lowering gout drug in more than 40 years. In August 2009, the FDA approved colchicine for the treatment of acute gout. Several other pharmaceutical companies are also conducting clinical trials to test new drugs for acute and chronic gout. This article reviews new drugs and drugs in development in the management of acute and chronic gout. |
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Authors:
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Naomi Schlesinger |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current rheumatology reports Volume: 12 ISSN: 1534-6307 ISO Abbreviation: Curr Rheumatol Rep Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-28 Completed Date: 2010-07-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888970 Medline TA: Curr Rheumatol Rep Country: United States |
Other Details:
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Languages: eng Pagination: 130-4 Citation Subset: IM |
Affiliation:
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Division of Rheumatology, Department of Medicine, University of Medicine and Dentistry of New Jersey/Robert Wood Johnson Medical School, One Robert Wood Johnson Place, New Brunswick, NJ 08903, USA. schlesna@umdnj.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Chronic Disease Colchicine / therapeutic use* Gout / drug therapy* Gout Suppressants / therapeutic use* Humans Hyperuricemia / drug therapy* Polyethylene Glycols / therapeutic use* Thiazoles / therapeutic use* Urate Oxidase / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Gout Suppressants; 0/Polyethylene Glycols; 0/Thiazoles; 0/polyethylene glycol-uricase; 144060-53-7/febuxostat; 64-86-8/Colchicine; EC 1.7.3.3/Urate Oxidase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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