Document Detail


New advances in the management of juvenile idiopathic arthritis--2: the era of biologicals.
MedLine Citation:
PMID:  19770495     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Juvenile idiopathic arthritis (JIA) is the most common paediatric rheumatic disease with significant long-term morbidity and mortality. Major advances have taken place in recent years in our understanding and the evidence base of JIA. The advent of biological therapies has opened a major new era in the medical management of JIA with recent trials published of etanercept, infliximab, adalimumab, abatacept, tocilizumab and anakinra. National and international collaborative clinical and research networks are ideally placed to enable future advances in the management of JIA and all paediatric rheumatic disorders. This review follows on from Part 1 of a review of recent advances in non-biological therapies in JIA, and focuses on the significant new advances in biological therapies in managing JIA.
Authors:
M W Beresford; E M Baildam
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Archives of disease in childhood. Education and practice edition     Volume:  94     ISSN:  1743-0593     ISO Abbreviation:  Arch Dis Child Educ Pract Ed     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-22     Completed Date:  2009-12-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101220684     Medline TA:  Arch Dis Child Educ Pract Ed     Country:  England    
Other Details:
Languages:  eng     Pagination:  151-6     Citation Subset:  IM    
Affiliation:
Institute of Child Health, Alder Hey Children's NHS Foundation Trust, University of Liverpool, Liverpool, UK. m.w.beresford@liverpool.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Monoclonal / therapeutic use*
Antirheumatic Agents / therapeutic use*
Arthritis, Juvenile Rheumatoid / drug therapy*
Biological Therapy*
Child
Humans
Chemical
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Antirheumatic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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