Document Detail

New Vectorcardiographic non-planarity measure of T-wave loop improves separation between healthy subjects and myocardial infarction patients.
MedLine Citation:
PMID:  19963764     Owner:  NLM     Status:  MEDLINE    
Principal component analysis of vectorcardio-graphic T-wave loop has been shown to be a potential tool to describe the abnormality of the cardiac repolarization and to predict cardiac events in patients with cardiac disease. In this paper a new method for estimating the non-planarity of the T-wave loop is introduced and tested with healthy subjects and subjects with anterior or inferior myocardial infarction. The method is based on the resamping of T-wave data points with respect to the arc-length, the total least squares plane fitting, the identifying and reordering of the fitted axes, and decomposing the optimal rotation matrix. A recently published related measure, PCA3, was used for comparison purposes. The results showed that the non-planarity of T-wave loop increased significantly in patients with myocardial infarction compared to the healthy group. The new method separated healthy and patient groups with p-value 0.002 while PCA3 only with p-value 0.075. The new method was superior to PCA3 in separating the healthy patients from both infarction types.
Mari Karsikas; Kai Noponen; Heikki Huikuri; Tapio Seppanen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2009     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2009  
Date Detail:
Created Date:  2009-12-07     Completed Date:  2010-03-25     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1754-7     Citation Subset:  IM    
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MeSH Terms
Case-Control Studies
Electrocardiography / methods*
Myocardial Infarction / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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