Document Detail

A "New Twist" on RGS Protein Selectivity.
MedLine Citation:
PMID:  23473665     Owner:  NLM     Status:  In-Data-Review    
G protein-coupled receptors mediate a wide array of physiologic stimuli and, together with their regulators such as RGS2, are essential components of cellular signaling and function. RGS2 is a selective inhibitor of the Gαq class of α subunits. In this issue of Structure, Nance and colleagues provide structural insight into the features of RGS2 that mediate its potent and selective regulation of Gαq function.
Scott P Heximer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Structure (London, England : 1993)     Volume:  21     ISSN:  1878-4186     ISO Abbreviation:  Structure     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-03-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101087697     Medline TA:  Structure     Country:  United States    
Other Details:
Languages:  eng     Pagination:  319-20     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 Elsevier Ltd. All rights reserved.
Department of Physiology, Heart and Stroke/Richard Lewar Centre of Excellence in Cardiovascular Research, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada. Electronic address:
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