| New Thrombolytic Agents: Does Direct Angioplasty Still Have a Role? | |
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MedLine Citation:
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PMID: 11096674 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The optimal method of reperfusion for patients with ST-segment elevation acute myocardial infarction has been a point of controversy over the last two decades. Tenecteplase and reteplase are comparable to accelerated-dose alteplase but more convenient because they can be delivered as a bolus. Combination regimens represent a further advance in reperfusion therapy; planned and ongoing studies will evaluate the clinical efficacy and safety of combination therapy. Promising early results of primary coronary intervention with glycoprotein IIb/IIIa receptor inhibition have been reported, and this strategy may emerge as a mainstay of therapy at hospitals with on-site interventional facilities. A possible future approach that could be universally applied consists of combination therapy and adjunctive/rescue percutaneous intervention in selected patients. |
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Authors:
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Llevadot; Giugliano |
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Publication Detail:
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Type: JOURNAL ARTICLE |
Journal Detail:
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Title: Current interventional cardiology reports Volume: 2 ISSN: 1534-3103 ISO Abbreviation: Curr Interv Cardiol Rep Publication Date: 2000 Aug |
Date Detail:
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Created Date: 2000-11-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888981 Medline TA: Curr Interv Cardiol Rep Country: - |
Other Details:
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Languages: ENG Pagination: 250-257 Citation Subset: - |
Affiliation:
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Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. rgiugliano@rics.bwh.harvard.edu |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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