Document Detail

A new software package for predictive gene regulatory network modeling and redesign.
MedLine Citation:
PMID:  23614576     Owner:  NLM     Status:  MEDLINE    
The efficacy of a newly created software package for predictive modeling of developmental gene regulatory networks (GRNs) has recently been demonstrated (Peter et al., 2012 ). The program GeNeTool computes spatial gene expression patterns based on GRN interactions and thereby allows the direct comparison of predicted and observed spatial expression patterns. GeNeTool also permits in silico exploration of both cis- and trans- perturbations of GRN interactions. Here, we present this program, review briefly its major features and applications, and provide a detailed and accessible tutorial.
Emmanuel Faure; Isabelle S Peter; Eric H Davidson
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Publication Detail:
Type:  Journal Article     Date:  2013-04-24
Journal Detail:
Title:  Journal of computational biology : a journal of computational molecular cell biology     Volume:  20     ISSN:  1557-8666     ISO Abbreviation:  J. Comput. Biol.     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-05-30     Completed Date:  2013-10-28     Revised Date:  2014-06-03    
Medline Journal Info:
Nlm Unique ID:  9433358     Medline TA:  J Comput Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  419-23     Citation Subset:  IM    
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MeSH Terms
Gene Expression Regulation, Developmental*
Gene Regulatory Networks*
Models, Genetic*

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