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A New Route to Indazolone via Amidation Reaction of o-Carboxyazobenzene.
MedLine Citation:
PMID:  22233207     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
One new route for the synthesis of amino-substituted indazol-3,5-dione via the amidation reaction of o-carboxyazobenzenes is reported. Optimization which includes effects of the solvents, molar ratio of starting materials, and dehydrating agents on this reaction has been studied. A possible reaction mechanism has been proposed on the basis of the product's structure, and the steric hindrance could be the main reason for low yield.
Authors:
Chengjie Li; Tianyi Zhang; Zhe Zeng; Xiujun Liu; Yunfeng Zhao; Bao Zhang; Yaqing Feng
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-10
Journal Detail:
Title:  Organic letters     Volume:  -     ISSN:  1523-7052     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
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