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A New Rosmarinic Acid Derivative from Isodon oresbius.
MedLine Citation:
PMID:  17260244     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Phytochemical reinvestigation of ISODON ORESBIUS afforded, in addition to oleanolic acid, ursolic acid, sodoponin, astragalin, and quercetin-3- O-glucoside, three known (oresbiusin A, rosmarinic acid and methyl rosmarinate) and a new rosmarinic acid derivative as well as an ENT-kaurene diterpenoid, neo-angustifolin, characterized as a separated component for the first time. By a combination of 1D- and 2D-NMR techniques the structure of the new compound was established as butyl rosmarinate. The IN VITRO antifungal assay showed that neoangustifolin was active against CANDIDA ALBICANS with the MIC being 50 microg/ml.
Authors:
H Huang; Q R Chao; R X Tan; H D Sun; D C Wang; J Ma; S X Zhao
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Planta medica     Volume:  65     ISSN:  0032-0943     ISO Abbreviation:  Planta Med.     Publication Date:  1999 Feb 
Date Detail:
Created Date:  2007-01-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0066751     Medline TA:  Planta Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  92-3     Citation Subset:  -    
Affiliation:
Department of Biological Science & Technology, Nanjing University, Nanjing, P.R. China (Present address: Institute of Organic Chemistry, Academia Sinica, Shanghai, China).
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