| A new role for cyclic phosphatidic acid as a PPARgamma antagonist. | |
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MedLine Citation:
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PMID: 20816085 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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A recent study in Molecular Cell (Tsukahara et al., 2010) identifies cyclic phosphatidic acid (CPA) as a naturally occurring PPARgamma antagonist that can be generated from lysophospholipids by signal-dependent activation of phospholipase D2. This endogenous CPA regulates PPARgamma functions required for adipogenesis, glucose homeostasis, and vascular wall biology. |
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Authors:
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Yumiko Oishi-Tanaka; Christopher K Glass |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cell metabolism Volume: 12 ISSN: 1932-7420 ISO Abbreviation: Cell Metab. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-09-06 Completed Date: 2010-11-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101233170 Medline TA: Cell Metab Country: United States |
Other Details:
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Languages: eng Pagination: 207-8 Citation Subset: - |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Cellular and Molecular Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0651, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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