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A New Iridoid Glycoside from the Roots of Dipsacus asper.
MedLine Citation:
PMID:  22306831     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A new iridoid glycoside, named loganic acid ethyl ester (1), together with five known compounds: chlorogenic acid (2), caffeic acid (3), loganin (4), cantleyoside (5) and syringaresinol-4',4''-O-bis-β-D-glucoside (6) were isolated from the roots of Dipsacus asper. The structure of compound 1 was elucidated on the basis of detailed spectroscopic analyses. Lignan is isolated from Dipsacaceae species for the first time. Compounds 1, 4 and 5 had moderate neuroprotective effects against the Aβ(25-35) induced cell death in PC12 cells.
Authors:
De Ji; Chunfeng Zhang; Jingzhi Li; Haowei Yang; Jingyang Shen; Zhonglin Yang
Publication Detail:
Type:  Journal Article     Date:  2012-02-03
Journal Detail:
Title:  Molecules (Basel, Switzerland)     Volume:  17     ISSN:  1420-3049     ISO Abbreviation:  Molecules     Publication Date:  2012  
Date Detail:
Created Date:  2012-02-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100964009     Medline TA:  Molecules     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  1419-24     Citation Subset:  IM    
Affiliation:
State Key Laboratory of Natural Products and Functions, China Pharmaceutical University, Ministry of Education, 24 Tong Jia Xiang, Nanjing 210009, China. yzl1950@tom.com.
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