| New family of peptidomimetics based on the imidazole motif. | |
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MedLine Citation:
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PMID: 20939523 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Starting from amino acid esters, new peptidomimetics based on the imidazole scaffold were prepared. An efficient and rapid sequence consisting of two subsequent one-pot procedures was developed and applied to various aminoacids. As they provide more substitution patterns, these heterocyclic mimics are promising tools for structural and biological studies. |
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Authors:
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Sylvain Petit; Corinne Fruit; Laurent Bischoff |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Organic letters Volume: 12 ISSN: 1523-7052 ISO Abbreviation: Org. Lett. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-29 Completed Date: 2011-01-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890393 Medline TA: Org Lett Country: United States |
Other Details:
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Languages: eng Pagination: 4928-31 Citation Subset: IM |
Affiliation:
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IRCOF-INSA Rouen-CNRS UMR 6014 COBRA, Université de Rouen, place Emile Blondel 76130 Mont-Saint-Aignan, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amides
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chemistry Aza Compounds / chemistry Imidazoles / chemistry* Molecular Structure Peptidomimetics / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Amides; 0/Aza Compounds; 0/Imidazoles; 0/Peptidomimetics; 288-32-4/imidazole |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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