| New Cannabinoid-Like Chromane and Chromene Derivatives from Rhododendron anthopogonoides. | |
| | |
MedLine Citation:
|
PMID: 22041081 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Two new cannabinoid-like chromane and chromene derivatives named anthopogocyclolic acid (1) and anthopogochromenic acid (2) and five related compounds (3-7) which are known as synthetic analogues of cannabinoids: cannabichromene (CBC) type, cannabicyclol (CBL) type, and cannabicitran (CBT) type, have been isolated together with geranyl orsellinic acid (8) from the Chinese medicinal plant Rhododendron anthopogonoides. Their structures were elucidated based on spectroscopic and chemical evidence. The absolute configuration of the asymmetric carbons at C-2 of 1-7 was determined to be S from their circular dichroism (CD) spectra. Compounds 2, 4 and 6 inhibited compound 48/80-induced histamine release from rat peritoneal mast cells. |
| | |
Authors:
|
Naoki Iwata; Susumu Kitanaka |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Chemical & pharmaceutical bulletin Volume: 59 ISSN: 1347-5223 ISO Abbreviation: Chem. Pharm. Bull. Publication Date: 2011 |
Date Detail:
|
Created Date: 2011-11-01 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0377775 Medline TA: Chem Pharm Bull (Tokyo) Country: Japan |
Other Details:
|
Languages: eng Pagination: 1409-12 Citation Subset: IM |
Affiliation:
|
School of Pharmacy, Nihon University. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Efficient improved extraction of tomato saponin using shock waves.
Next Document: Cytotoxicity of New 5-Phenyl-4,5-dihydro-1,3,4-thiadiazole Analogues.