| New 7,20:14,20-diepoxy ent-kauranoids from Isodon xerophilus. | |
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MedLine Citation:
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PMID: 10843567 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Three new 7,20:14,20-diepoxy-ent-kaurane diterpenoids, xerophilusins A-C (1-3), together with a known one, macrocalin B (4), were isolated from the leaves of Isodon xerophilus. Their structures were elucidated on the basis of their spectral properties and X-ray crystallographic analysis. Compounds 1, 2, and 4 showed significant cytotoxic activity against K562, HL-60, and MKN-28 cells. |
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Authors:
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A J Hou; M L Li; B Jiang; Z W Lin; S Y Ji; Y P Zhou; H D Sun |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of natural products Volume: 63 ISSN: 0163-3864 ISO Abbreviation: J. Nat. Prod. Publication Date: 2000 May |
Date Detail:
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Created Date: 2000-07-31 Completed Date: 2000-07-31 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7906882 Medline TA: J Nat Prod Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 599-601 Citation Subset: IM |
Affiliation:
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Laboratory of Phytochemistry, Kunming Institute of Botany, Academia Sinica, Kunming 650204, Yunnan, People's Republic of China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antineoplastic Agents, Phytogenic
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pharmacology Crystallography, X-Ray Diterpenes / chemistry, isolation & purification*, pharmacology Drug Screening Assays, Antitumor Humans Mitoxantrone / pharmacology Plant Leaves / chemistry Plants, Medicinal / chemistry* Tumor Cells, Cultured |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents, Phytogenic; 0/Diterpenes; 0/xerophilusin A; 0/xerophilusin B; 0/xerophilusin C; 65271-80-9/Mitoxantrone; 93781-75-0/macrocalin B |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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