Document Detail

Nevi and melanoma: lessons from Turner's syndrome.
MedLine Citation:
PMID:  11244219     Owner:  NLM     Status:  MEDLINE    
Females with Turner's syndrome (TS) have a markedly increased number of cutaneous nevi. While this is a well-recognized risk factor for cutaneous melanoma (CM), the incidence of this tumor in TS and the implications for our understanding of nevi and melanoma have not previously been considered. Here we report a case of an anorectal melanoma in a woman with TS and a review of the literature. Overall, there appears to be a lower than expected incidence of CM. Possible explanations are discussed and in particular the possible relationship between sex hormones and melanoma development as these girls fail to undergo normal pubertal development. Further study of this syndrome may provide important insights into the genetic factors involved in normal melanocyte and nevus development, the potential influence of sex hormones on melanoma development and the relationship between the presence of nevi and the risk of developing CM.
P Gibbs; B M Brady; R Gonzalez; W A Robinson
Related Documents :
2404559 - Malignant paraganglioma of the posterior mediastinum. a case report and review of the l...
2403779 - Kaposi's sarcoma in transfusion-associated acquired immunodeficiency syndrome. a case r...
16150209 - Pigmented epithelioid melanocytoma: two case reports.
24035669 - Are youtube seizure videos misleading? neurologists do not always agree.
17113519 - Multiple malignant melanomas in association with neurofibromatosis type 1.
17343569 - Utility of sentinel node biopsy in vulvar and vaginal melanoma: report of two cases and...
19024199 - Departmental audit of malaria control programme 2001-2005 north west frontier province ...
24431729 - Resilient liners: a review.
10808749 - Malaria in the limbé river valley of northern haiti: a hospital-based retrospective st...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Dermatology (Basel, Switzerland)     Volume:  202     ISSN:  1018-8665     ISO Abbreviation:  Dermatology (Basel)     Publication Date:  2001  
Date Detail:
Created Date:  2001-03-13     Completed Date:  2001-05-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9203244     Medline TA:  Dermatology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  1-3     Citation Subset:  IM    
University of Colorado Health Sciences Center, Denver, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Melanoma / complications*,  pathology
Nevus / complications*,  pathology
Skin Neoplasms / complications*,  pathology
Turner Syndrome / complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Interrater reliability of the modified Jadad quality scale for systematic reviews of Alzheimer's dis...
Next Document:  Atopic signs and symptoms: assessing the 'atopy score' concept.