Document Detail

Neutrophil to lymphocyte ratio and cardiovascular diseases: a review.
MedLine Citation:
PMID:  23259445     Owner:  NLM     Status:  MEDLINE    
The role of inflammatory markers in cardiovascular diseases has been studied extensively and a consistent relationship between various inflammatory markers and cardiovascular diseases has been established in the past. Neutrophil to lymphocyte ratio (NLR) is a new addition to the long list of these inflammatory markers. NLR, which is calculated from complete blood count with differential, is an inexpensive, easy to obtain, widely available marker of inflammation, which can aid in the risk stratification of patients with various cardiovascular diseases in addition to the traditionally used markers. It has been associated with arterial stiffness and high coronary calcium score, which are themselves significant markers of cardiovascular disease. NLR is reported as an independent predictor of outcome in stable coronary artery disease, as well as a predictor of short- and long-term mortality in patients with acute coronary syndromes. It is linked with increased risk of ventricular arrhythmias during percutaneous coronary intervention (PCI) and higher long-term mortality in patients undergoing PCI irrespective of indications of PCI. In patients admitted with advanced heart failure, high NLR was reported with higher inpatient mortality. Recently, NLR has been reported as a prognostic marker for outcome from coronary artery bypass grafting and postcoronary artery bypass grafting atrial fibrillation.
Tariq Bhat; Sumaya Teli; Jharendra Rijal; Hilal Bhat; Muhammad Raza; Georges Khoueiry; Mustafain Meghani; Muhammad Akhtar; Thomas Costantino
Related Documents :
23016715 - Insight to the pathophysiology of stable angina pectoris.
22254715 - Effect of atrioventricular conduction on heart rate variability.
8681155 - Psychological predictors of subsequent medical care among patients hospitalized with ca...
2353615 - Perioperative and long-term prognostic value of intravenous dipyridamole thallium scint...
12029205 - Cardiac 123 i-mibg imaging and clinical variables in risk stratification in patients wi...
8313425 - Quantification of myocardium at risk and detection of reperfusion by dynamic vectorcard...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Expert review of cardiovascular therapy     Volume:  11     ISSN:  1744-8344     ISO Abbreviation:  Expert Rev Cardiovasc Ther     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-12-24     Completed Date:  2013-05-28     Revised Date:  2014-05-27    
Medline Journal Info:
Nlm Unique ID:  101182328     Medline TA:  Expert Rev Cardiovasc Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  55-9     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Biological Markers / blood
Cardiovascular Diseases / blood,  diagnosis,  immunology*
Leukocyte Count
Lymphocytes / immunology*
Neutrophils / immunology*
Reg. No./Substance:
0/Biological Markers
Comment In:
Expert Rev Cardiovasc Ther. 2014 May;12(5):539-40   [PMID:  24749924 ]
Expert Rev Cardiovasc Ther. 2014 May;12(5):537-8   [PMID:  24745892 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Feasibility and clinical implementation of hand-held echocardiography.
Next Document:  Metabolomic profiling as a useful tool for diagnosis and treatment of chronic disease: focus on obes...