Document Detail


Neutrophil functions of Chinese neonates.
MedLine Citation:
PMID:  10760014     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To delineate neutrophil function of preterm and full-term neonates of Chinese origin. METHODS: Chinese neonates admitted to two major Hong Kong neonatal units were randomly selected for the study. Candidacidal activity, phagocytosis, chemotaxis and nitroblue tetrazolium reduction scores were evaluated from blood. RESULTS: Except for chemotactic activity, the neutrophil functions of Chinese preterm neonates were similar to Chinese full-term neonates. The candidacidal activity of males was significantly lower when compared with female neonates. Compared with adult controls, both term and preterm infants had similar phagocytic activities although their candidacidal activities and chemotactic index were significantly decreased. Neutrophil function of Chinese infants was nearer to that of adult controls than historically reported for western infants. CONCLUSION:: Preterm Chinese neonates had similar neutrophil function to full-term infants. Neutrophil function of Chinese infants was more mature than that of western infants.
Authors:
T Wan; C Yeung; A Tam
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  36     ISSN:  1034-4810     ISO Abbreviation:  J Paediatr Child Health     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-05-08     Completed Date:  2000-05-08     Revised Date:  2007-09-24    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  153-8     Citation Subset:  IM    
Affiliation:
Department of Paediatrics, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China.
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MeSH Terms
Descriptor/Qualifier:
Adult
Candida albicans / growth & development,  immunology
Chemotaxis, Leukocyte
Female
Hong Kong
Humans
Infant, Newborn
Male
Neutrophils / immunology*,  microbiology
Nitroblue Tetrazolium
Phagocytosis
Chemical
Reg. No./Substance:
298-83-9/Nitroblue Tetrazolium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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