Document Detail


Neutrophil-Lymphocyte Ratio and the Platelet-Lymphocyte Ratio Predict the Limb Survival in Critical Limb Ischemia.
MedLine Citation:
PMID:  23393289     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background: The objective of this study was to evaluate whether admission neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) might reflect amputation in patients with critical limb ischemia (CLI) who could not get surgical or radiological (percutaneous transluminal angioplasty) revascularization. Methods: A total of 104 patients with nonreconstructable CLI over a 5-year period were collected prospectively. Results: Admission NLR levels of ≥3.2 and a PLR of ≥160 were found to represent the optimal cutoff values to risk stratification of patients. If both levels were elevated, patients had a median overall limb survival of 22 months. For cases where both levels were less than the cutoff values, the median overall limb survival time was not reached but was greater than 60 months. Conclusions: Admission NLR and PLR both merit further evaluation as prognostic indices in patients with CLI.
Authors:
Irfan Tasoglu; Dogan Sert; Necmettin Colak; Alper Uzun; Murat Songur; Ata Ecevit
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-6
Journal Detail:
Title:  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis     Volume:  -     ISSN:  1938-2723     ISO Abbreviation:  Clin. Appl. Thromb. Hemost.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-2-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508125     Medline TA:  Clin Appl Thromb Hemost     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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