Document Detail


Neutrophil CD64 as a diagnostic marker in neonatal sepsis.
MedLine Citation:
PMID:  22481422     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We assessed neutrophil CD64 as a diagnostic marker for neonatal sepsis. For early-onset sepsis, the CD64 index with a cut-point value of 2.38 had sensitivity, specificity and negative predictive values of 100%, 68% and 100%, respectively. For late-onset sepsis, the respective values were 3.62, 75%, 77% and 96%. Neutrophil CD64 index can be incorporated as a valuable marker for excluding neonatal sepsis.
Authors:
Iris Streimish; Matthew Bizzarro; Veronika Northrup; Chao Wang; Sara Renna; Nancy Koval; Fang-Yong Li; Richard Ehrenkranz; Henry M Rinder; Vineet Bhandari
Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  31     ISSN:  1532-0987     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-06-14     Completed Date:  2012-10-02     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  777-81     Citation Subset:  IM    
Affiliation:
Division of Perinatal Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA.
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MeSH Terms
Descriptor/Qualifier:
Biological Markers / blood
Female
Humans
Infant, Newborn
Male
Neutrophils / chemistry*
Predictive Value of Tests
Receptors, IgG / analysis*
Sensitivity and Specificity
Sepsis / diagnosis*,  pathology*
Grant Support
ID/Acronym/Agency:
UL1 RR024139/RR/NCRR NIH HHS; UL1 RR024139/RR/NCRR NIH HHS; UL1 TR000142/TR/NCATS NIH HHS
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Receptors, IgG
Comments/Corrections

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