Document Detail


Neutropenia in infants with hemolytic disease of the newborn.
MedLine Citation:
PMID:  21721107     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: This study examined the incidence, outcome and risk factors of neutropenia in infants with hemolytic disease of the newborn (HDN). METHODS: A retrospective chart review was performed on infants with HDN. RESULTS: Of 69 evaluable infants, 45% developed neutropenia. Only one infectious complication was recorded. In most instances the neutropenia resolved spontaneously, but in seven infants it persisted for a median of 397 days. Males were at higher risk for developing neutropenia, but severity of HDN, antibody specificity, or therapy were not significant risk factors. CONCLUSIONS: Neutropenia is a common feature of HDN, regardless of severity of disease, treatment received, or antibody specificity. Pediatr Blood Cancer © 2011 Wiley-Liss, Inc.
Authors:
Esther Blanco; Donna L Johnston
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-30
Journal Detail:
Title:  Pediatric blood & cancer     Volume:  -     ISSN:  1545-5017     ISO Abbreviation:  -     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-7-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101186624     Medline TA:  Pediatr Blood Cancer     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Wiley-Liss, Inc.
Affiliation:
Division of Hematology/Oncology, Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
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