| Neutralizing influenza antibodies, IgA and total protein in the nasopharyngeal secretions of subjects vaccinated by nasal route with the inactivated influenza vaccine prepared in the "Stefan S. Nicolau" Institute of Virology. | |
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MedLine Citation:
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PMID: 111408 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Intranasal administration of two doses of the inactivated influenza vaccine prepared in the "Stefan S. Nicolau" Institute of Virology was followed by rises in the level of neutralizing secretory influenza antibodies in 82% of the cases. The concomitant study of secretory antibody, IgA and total protein levels, as well as of the serum HAI influenza antibodies demonstrated that their evolution was parallel only in 23% of the vaccinees. The percentage of secretory antibody conversion was similar to the rate of protection conferred by the vaccine. |
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Authors:
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A Petrescu; A Mihail; I Samuel; O Teodosiu; G Isaia; E Ganea; C Motaş |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Virologie Volume: 30 ISSN: 0253-181X ISO Abbreviation: Virologie Publication Date: 1979 Apr-Jun |
Date Detail:
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Created Date: 1979-09-25 Completed Date: 1979-09-25 Revised Date: 2013-05-07 |
Medline Journal Info:
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Nlm Unique ID: 7605765 Medline TA: Virologie Country: ROMANIA |
Other Details:
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Languages: eng Pagination: 109-15 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Intranasal Antibodies, Viral / analysis* Antibody Formation Blood Proteins / analysis Humans Immunodiffusion Immunoglobulin A / metabolism* Immunoglobulin A, Secretory / metabolism* Influenza Vaccines / administration & dosage* Influenza, Human / immunology*, prevention & control Nasopharynx / analysis, immunology |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Viral; 0/Blood Proteins; 0/Immunoglobulin A; 0/Immunoglobulin A, Secretory; 0/Influenza Vaccines |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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