| Neutralization antibody responses induced by Japanese encephalitis virus vaccine. | |
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MedLine Citation:
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PMID: 7346039 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Single doses of Japanese encephalitis (JE) vaccine of the Nakayama strain were given to members of the staffs of a hospital and 99 paired-sera were obtained. Neutralization antibody titers of the sera were determined against the Nakayama strain and E-50 strain, isolated from wild Culex tritaeniorhynchus using clone C6/36 of Singh's Aedes albopictus mosquito cell culture. Post-vaccination sera showed a significant neutralizing antibody response against both the Nakayama and E-50 strain. The geometrical mean neutralization titers of post-vaccination sera against the Nakayama and E-50 strains were in the same order, although the geometrical mean neutralization titer against the Nakayama strain was the higher in pre-vaccination sera. The antibody responses against the Nakayama strain and E-50 strain were somewhat different in detail: 7 individuals with a pre-vaccination neutralization titers of less than 10 showed antibody responses to the Nakayama strain, whereas 3 individuals of the same group did not show any detectable response to the E-50 strain. |
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Authors:
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S Susilowati; Y Okuno; T Fukunaga; M Tadano; R F Juang; K Fukai |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Biken journal Volume: 24 ISSN: 0006-2324 ISO Abbreviation: Biken J Publication Date: 1981 Dec |
Date Detail:
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Created Date: 1982-09-24 Completed Date: 1982-09-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0373117 Medline TA: Biken J Country: JAPAN |
Other Details:
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Languages: eng Pagination: 137-45 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antibody Formation* Cross Reactions Encephalitis Virus, Japanese / immunology* Humans Neutralization Tests Species Specificity Viral Vaccines / immunology* |
| Chemical | |
Reg. No./Substance:
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0/Viral Vaccines |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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