Document Detail


Neutral amino acid transport during the cell cycle of cultured human lymphocytes.
MedLine Citation:
PMID:  7217224     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Neutral amino acid (isoleucine, leucine, and valine) transport was monitored in synchronous populations of WIL-2 cells, a diploid human lymphoblastoid B cell line. Cells were synchronized by either the double thymidine block technique or by density-dependent arrest in G1. Cells synchronized by these methods showed up to a 66% decrease in amino acid transport upon progressing from the early S phase through the G2 and M phases with a concomitant increase in transport during the G1 phase. The lowest activities of amino acid transport in synchronized cells were observed during the G2 and M phases.
Authors:
M C Glassy; C E Furlong
Related Documents :
9207224 - Association of protein phosphatase-1delta with the retinoblastoma protein and reversibl...
11295494 - Genetic dissection of the yeast 26s proteasome: cell cycle defects caused by the deltar...
22300744 - Ion-induced cell sheet detachment from standard cell culture surfaces coated with polye...
3693414 - Messenger rnas coding for enzymes of polyamine biosynthesis are induced during the g0-g...
17284294 - Effect of interictal spikes on single-cell firing patterns in the hippocampus.
11486174 - Follicular dendritic cell tumor presenting in the lung: a case report.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of cellular physiology     Volume:  107     ISSN:  0021-9541     ISO Abbreviation:  J. Cell. Physiol.     Publication Date:  1981 Apr 
Date Detail:
Created Date:  1981-06-13     Completed Date:  1981-06-13     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0050222     Medline TA:  J Cell Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  69-74     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Amino Acids, Branched-Chain / metabolism*
Biological Transport
Cell Cycle*
Cell Wall
Cells, Cultured
Humans
Isoleucine / metabolism
Leucine / metabolism
Lymphocytes / metabolism*
Valine / metabolism
Grant Support
ID/Acronym/Agency:
GM-15258/GM/NIGMS NIH HHS; GM-18311/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Amino Acids, Branched-Chain; 61-90-5/Leucine; 7004-03-7/Valine; 73-32-5/Isoleucine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The reversible inability of isoproterenol-activated parotid gland cells to initiate DNA synthesis in...
Next Document:  Cation transport and growth regulation in neuroblastoma cells. Modulations of K+ transport and elect...