Document Detail


Neutral lipid storage leads to acylceramide deficiency, likely contributing to the pathogenesis of Dorfman-Chanarin syndrome.
MedLine Citation:
PMID:  20520629     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Authors:
Yoshikazu Uchida; Yunhi Cho; Sam Moradian; Jungmin Kim; Kimiko Nakajima; Debra Crumrine; Kyungho Park; Mayumi Ujihara; Masashi Akiyama; Hiroshi Shimizu; Walter M Holleran; Shigetoshi Sano; Peter M Elias
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Publication Detail:
Type:  Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2010-06-03
Journal Detail:
Title:  The Journal of investigative dermatology     Volume:  130     ISSN:  1523-1747     ISO Abbreviation:  J. Invest. Dermatol.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-15     Completed Date:  2010-10-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0426720     Medline TA:  J Invest Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2497-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
1-Acylglycerol-3-Phosphate O-Acyltransferase / genetics*,  metabolism
Ceramides / deficiency*
Humans
Ichthyosis / genetics,  metabolism*
Lipid Metabolism / physiology*
Lipid Metabolism, Inborn Errors / genetics,  metabolism*
Syndrome*
Grant Support
ID/Acronym/Agency:
AR051077/AR/NIAMS NIH HHS
Chemical
Reg. No./Substance:
0/Ceramides; EC 2.3.1.51/1-Acylglycerol-3-Phosphate O-Acyltransferase; EC 2.3.1.51/ABHD5 protein, human

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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