| Neurotrophins and acupuncture. | |
| | |
MedLine Citation:
|
PMID: 20451467 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The aim of this review is to report recent findings and ongoing studies on the effects of acupuncture on endogenous biological mediators, in particular on neurotrophins such as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). Acupuncture is a therapeutic technique and is a part of Traditional Chinese Medicine (TCM). Western descriptions of the clinical efficacy of acupuncture on pain, inflammation, motor dysfunction, mood disorders, and seizures are based on the stimulation of several classes of sensory afferent fibers and the consequent activation of physiological processes similar to those resulting from physical exercise or deep massage. The established research on the neuro-physiological correlates of acupuncture has pointed towards endogenous opioids as the principal biological mediators of the therapeutic actions of this ancient technique. More recently, several classes of molecules, such as neurotransmitters, cytokines and growth factors, have also been identified as possible mediators for specific acupuncture effects. This review will focus on the links between acupuncture and a class of growth factors known as neurotrophins (NTs), which are the main mediators of neural activity, plasticity and repair following neurodegeneration and/or traumatic injury. A special emphasis will be placed on the work of our laboratory investigating the role of nerve growth factor (NGF), the prototypical member of the neurotrophin family, as a mediator of acupuncture effects in the central nervous system (CNS) and as a modulator of sensory and autonomic activity. |
| | |
Authors:
|
Luigi Manni; Marcello Albanesi; Morena Guaragna; Samuele Barbaro Paparo; Luigi Aloe |
Related Documents
:
|
16547277 - Il-4-induced peroxisome proliferator-activated receptor gamma activation inhibits nf-ka... 16155637 - Different expression of macrophages and microglia in rat spinal cord contusion injury m... 14985427 - Oxidized galectin-1 stimulates macrophages to promote axonal regeneration in peripheral... 11304557 - The clinical course of experimental autoimmune encephalomyelitis and inflammation is co... 8572937 - Low levels of poliovirus replication in primary human monocytes: possible interactions ... 3903767 - Osteoporosis: a bone morphogenetic protein auto-immune disorder. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2010-05-07 |
Journal Detail:
|
Title: Autonomic neuroscience : basic & clinical Volume: 157 ISSN: 1872-7484 ISO Abbreviation: Auton Neurosci Publication Date: 2010 Oct |
Date Detail:
|
Created Date: 2010-10-18 Completed Date: 2011-02-02 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100909359 Medline TA: Auton Neurosci Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 9-17 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 Elsevier B.V. All rights reserved. |
Affiliation:
|
Institute of Neurobiology and Molecular Medicine, CNR, Rome, Italy. luigi.manni@inmm.cnr.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acupuncture* Animals Brain-Derived Neurotrophic Factor / metabolism* Humans Inflammation / therapy Mood Disorders / therapy Nerve Growth Factors / metabolism* Nervous System / metabolism* Pain / therapy Seizures / therapy |
| Chemical | |
Reg. No./Substance:
|
0/Brain-Derived Neurotrophic Factor; 0/Nerve Growth Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Sustained nociceptive mechanical stimulation of latent myofascial trigger point induces central sens...
Next Document: Autonomic predictors of recovery following surgery: A comparative study.