Document Detail


Neurotransmission in the human labyrinth.
MedLine Citation:
PMID:  11885650     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Different neuroactive substances have been found in the efferent pathways of both the olivocochlear and vestibular systems. In the present study, the distribution and role of three neurotransmitters, choline acetyltransferase (ChAT), gamma aminobutyric acid (GABA), and enkephalin were investigated in the human labyrinth of 4 normal-hearing individuals. Immunohistochemical studies in human inner ear research, however, face a problem of procuring well-preserved specimens with maintained neurotransmitter antigenicity and morphology. Methods and findings are reported and discussed.
Authors:
Anneliese Schrott-Fischer; Keren Kammen-Jolly; Arne W Scholtz; Wei-jia Kong; Michel Eybalin
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in oto-rhino-laryngology     Volume:  59     ISSN:  0065-3071     ISO Abbreviation:  Adv. Otorhinolaryngol.     Publication Date:  2002  
Date Detail:
Created Date:  2002-03-11     Completed Date:  2002-08-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0242534     Medline TA:  Adv Otorhinolaryngol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  11-7     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology, University of Innsbruck, Austria. Annelies.Schrott@uibk.ac.at
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MeSH Terms
Descriptor/Qualifier:
Choline O-Acetyltransferase / metabolism
Ear, Inner / metabolism,  physiology*
Enkephalins / metabolism
Hair Cells, Auditory / enzymology
Humans
Immunohistochemistry
Neurons, Afferent / enzymology,  ultrastructure
Neurons, Efferent / physiology
Organ of Corti / enzymology,  ultrastructure
Spiral Ganglion / enzymology,  ultrastructure
Synaptic Transmission / physiology*
gamma-Aminobutyric Acid / metabolism
Chemical
Reg. No./Substance:
0/Enkephalins; 56-12-2/gamma-Aminobutyric Acid; EC 2.3.1.6/Choline O-Acetyltransferase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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