Document Detail

Neurotoxicities in infants seen with the consumption of star anise tea.
MedLine Citation:
PMID:  15492355     Owner:  NLM     Status:  MEDLINE    
Chinese star anise (Illicium verum Hook f.) is a well-known spice used in many cultures. Many populations use it as a treatment for infant colic. Japanese star anise (Illicium anisatum L), however, has been documented to have both neurologic and gastrointestinal toxicities. Recently, concern has been raised regarding the adulteration of Chinese star anise with Japanese star anise. We report 7 cases of adverse neurologic reactions in infants seen with the home administration of star anise tea. In addition, we have found evidence that Chinese star anise has been contaminated with Japanese star anise. More strict federal regulation of the import of star anise into the United States is warranted. Star anise tea should no longer be administered to infants because of its potential danger in this population.
Diego Ize-Ludlow; Sean Ragone; Isaac S Bruck; Jeffrey N Bernstein; Michael Duchowny; Barbara M Garcia Peña
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2004-10-18
Journal Detail:
Title:  Pediatrics     Volume:  114     ISSN:  1098-4275     ISO Abbreviation:  Pediatrics     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-11-02     Completed Date:  2005-03-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e653-6     Citation Subset:  AIM; IM    
Department of Pediatrics, Miami Children's Hospital, Miami, FL 33155, USA.
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MeSH Terms
Colic / drug therapy*
Food Contamination*
Illicium / adverse effects*,  chemistry
Infant, Newborn
Neurotoxicity Syndromes / etiology*
Phytotherapy / adverse effects*
Plant Preparations / adverse effects
Tea / adverse effects*,  chemistry
Reg. No./Substance:
0/Plant Preparations; 0/Tea

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