| Neurotoxic effects in patients poisoned with organophosphorus pesticides. | |
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MedLine Citation:
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PMID: 21787602 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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In this paper we review neurotoxic disorders appearing in patients poisoned with organophosphorus pesticides. These compounds cause four important neurotoxic effects in humans: the cholinergic syndrome, the intermediate syndrome, organophosphate-induced delayed polyneuropathy (OPIDP) and chronic organophosphate-induced neuropsychiatric disorder (COPIND). Compared to the cholinergic syndrome, that causes millions of cases of poisoning each year, other disorders involve much smaller numbers of patients. The review is focused on the neurotoxic effects appearing after acute and chronic exposure to organophosphates with emphasis on clinical presentation, pathogenesis, molecular mechanisms, and possibilities for prevention/therapy. |
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Authors:
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Milan Jokanović; Melita Kosanović |
Publication Detail:
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Type: Journal Article Date: 2010-02-02 |
Journal Detail:
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Title: Environmental toxicology and pharmacology Volume: 29 ISSN: 1872-7077 ISO Abbreviation: Environ. Toxicol. Pharmacol. Publication Date: 2010 May |
Date Detail:
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Created Date: 2011-07-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9612020 Medline TA: Environ Toxicol Pharmacol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 195-201 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier B.V. All rights reserved. |
Affiliation:
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Faculty of Medicine, University of Nish, Nish, Serbia; Academy of Sciences and Arts of Republic Srpska, Banja Luka, Bosnia and Herzegovina. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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