Document Detail

Neurosurgical stress and immune function.
MedLine Citation:
PMID:  7779742     Owner:  NLM     Status:  MEDLINE    
The present study was carried out in 31 neurosurgical patients with unaffected consciousness and concerned by the severity of their condition. The severity of stress was established by the comparison between the pre- and postoperative peripheral blood lymphocyte populations and subpopulations (B, T, Th lymphocytes, serum complement and circulating immune complexes). The peripheral blood lymphocyte populations and subpopulations were determined by the technique of sheep red blood cell rosette. Circulating immune complexes were determined by precipitation of polyethylene glycol (PEG, M = 6000) whereas the serum complement by the usual 50% hemolytic method. Our data show that the decrease in Th cells and the consecutive diminution of antibody production is a cause of lower resistance against cancer and infections.
L Dănăilă; M Golu; G Coman; N Ruşcă
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Romanian journal of neurology and psychiatry = Revue roumaine de neurologie et psychiatrie     Volume:  32     ISSN:  1017-5644     ISO Abbreviation:  Rom J Neurol Psychiatry     Publication Date:    1994 Oct-Dec
Date Detail:
Created Date:  1995-07-19     Completed Date:  1995-07-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9014562     Medline TA:  Rom J Neurol Psychiatry     Country:  ROMANIA    
Other Details:
Languages:  eng     Pagination:  231-6     Citation Subset:  IM    
Clinic of Neurosurgery, Dr. G. Marinescu Hospital, Bucharest, Romania.
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MeSH Terms
Antigen-Antibody Complex / blood
B-Lymphocytes / immunology
Complement System Proteins / analysis
Middle Aged
Neuroimmunomodulation / immunology*
Neurosurgery / psychology*
Postoperative Period
Stress, Psychological / immunology*
T-Lymphocytes / immunology
Reg. No./Substance:
0/Antigen-Antibody Complex; 9007-36-7/Complement System Proteins

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