Document Detail

Neurostimulation: vagus nerve stimulation and beyond.
MedLine Citation:
PMID:  22062943     Owner:  NLM     Status:  In-Data-Review    
Patients with medically intractable epilepsy who are not candidates for epilepsy surgery could benefit from neurostimulation. At this time, vagus nerve stimulation (VNS) therapy is the only Food and Drug Administation-approved neurostimulation modality; it has been shown to be efficacious and just as well tolerated in children and adolescents as in adults. Notwithstanding the initial cost of the device and implantation, VNS therapy has been shown to be a cost-effective treatment, reducing direct medical costs and improving health-related quality of life measures. Deep brain stimulation of various brain regions, especially the anterior nucleus of the thalamus and responsive neurostimulation, also appear effective but are not yet approved for clinical use. Repetitive transcranial magnetic stimulation, which is also in early clinical development, is promising and could become available in the not too distant future.
Prakash Kotagal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Seminars in pediatric neurology     Volume:  18     ISSN:  1558-0776     ISO Abbreviation:  Semin Pediatr Neurol     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-11-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9441351     Medline TA:  Semin Pediatr Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  186-94     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Cleveland Clinic Epilepsy Center, Cleveland, OH.
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