| Neurostimulation: vagus nerve stimulation and beyond. | |
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MedLine Citation:
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PMID: 22062943 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Patients with medically intractable epilepsy who are not candidates for epilepsy surgery could benefit from neurostimulation. At this time, vagus nerve stimulation (VNS) therapy is the only Food and Drug Administation-approved neurostimulation modality; it has been shown to be efficacious and just as well tolerated in children and adolescents as in adults. Notwithstanding the initial cost of the device and implantation, VNS therapy has been shown to be a cost-effective treatment, reducing direct medical costs and improving health-related quality of life measures. Deep brain stimulation of various brain regions, especially the anterior nucleus of the thalamus and responsive neurostimulation, also appear effective but are not yet approved for clinical use. Repetitive transcranial magnetic stimulation, which is also in early clinical development, is promising and could become available in the not too distant future. |
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Authors:
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Prakash Kotagal |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Seminars in pediatric neurology Volume: 18 ISSN: 1558-0776 ISO Abbreviation: Semin Pediatr Neurol Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-11-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9441351 Medline TA: Semin Pediatr Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 186-94 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Cleveland Clinic Epilepsy Center, Cleveland, OH. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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