Document Detail

MedLine Citation:
PMID:  18539239     Owner:  NLM     Status:  MEDLINE    
Although neurosarcoidosis seems to occur in only 5% to 10% of patients who have sarcoidosis, it may lead to significant complications. The diagnosis of neurosarcoidosis usually relies on indirect information from imaging and spinal fluid examination. Although MR imaging remains the most sensitive technique for detecting neurologic disease, other tests, including positron emission tomography scanning and cerebral spinal fluid examination, can provide important information. The role of immunosuppressive agents such as methotrexate, cyclophosphamide, and azathioprine has been expanded, and these agents should be considered for the treatment of some manifestations of neurosarcoidosis. Reports of the antitumor necrosis factor agent infliximab suggest that this drug can be helpful for patients who have neurosarcoidosis.
Elyse E Lower; Kenneth L Weiss
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinics in chest medicine     Volume:  29     ISSN:  0272-5231     ISO Abbreviation:  Clin. Chest Med.     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-06-09     Completed Date:  2008-09-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7907612     Medline TA:  Clin Chest Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  475-92, ix     Citation Subset:  IM    
Interstitial Lung Disease and Sarcoidosis Center, University of Cincinnati Medical Center, 3235 Eden Avenue, Cincinnati, OH 45267, USA.
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MeSH Terms
Combined Modality Therapy / methods
Diagnosis, Differential
Diagnostic Imaging / methods
Nervous System Diseases / diagnosis*,  therapy*
Sarcoidosis / diagnosis*,  therapy*

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