Document Detail


Neurosarcoidosis affecting the vagus nerve.
MedLine Citation:
PMID:  21033034     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: Our objective was to review patients who presented to our medical center with a diagnosis of neurosarcoidosis affecting the vagus nerve and to present symptoms, progression, treatments, and outcome.
METHODS: We performed a chart review of patients who presented to our medical center in the past 10 years with a diagnosis of neurosarcoidosis specifically affecting cranial nerve X.
RESULTS: A chart review of 53 patients revealed only 4 with findings suggestive of vagal neurosarcoidosis. All were male and had a mean age of 50 years (range, 42 to 57 years) at presentation of symptoms. Two of the 4 patients presented initially with cough, 1 had recurrent syncope, and another presented with left facial pain. Vagus nerve involvement included vocal fold paresis or paralysis in all 4 patients, 2 of whom reported coughing with exposure to various odors and 2 of whom were found to have a unilateral palatal weakness. All but 1 had positive findings on magnetic resonance imaging of the head.
CONCLUSIONS: Neurosarcoidosis involving the vagus nerve is a rare finding, but should be considered in the differential diagnosis of vocal fold paresis or paralysis.
Authors:
Eran E Alon; Dale C Ekbom
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of otology, rhinology, and laryngology     Volume:  119     ISSN:  0003-4894     ISO Abbreviation:  Ann. Otol. Rhinol. Laryngol.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-10-27     Completed Date:  2010-11-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0407300     Medline TA:  Ann Otol Rhinol Laryngol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  641-5     Citation Subset:  AIM; IM    
Affiliation:
Dept of Otolaryngology-Head and Neck Surgery, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Biopsy
Cough / etiology
Diagnosis, Differential
Facial Pain / etiology
Humans
Lymph Nodes / pathology
Magnetic Resonance Imaging*
Male
Middle Aged
Sarcoidosis / diagnosis*,  genetics,  pathology
Syncope / etiology
Vagus Nerve Diseases / diagnosis*,  pathology
Vocal Cord Paralysis / diagnosis,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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