Document Detail


Neuroradiologic findings in a young patient with characteristics of Sturge-Weber syndrome and Klippel-Trenaunay syndrome.
MedLine Citation:
PMID:  16417862     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The patient presented here has extensive hemangiomata plana, especially on the right forehead, right upper eyelid, and right leg, as well as right leg hypertrophy and macrocephaly. Cerebral magnetic resonance imaging (MRI) showed abnormalities in only one occipital lobe consisting of focal cortical atrophy, leptomeningeal enhancement, and ipsilateral choroid plexus enlargement. Mental and motor development is normal, and he has no seizures. The parents are consanguineous. Leg hypertrophy associated with ipsilateral cutaneous vascular malformations is suggestive of Klippel-Trenaunay syndrome. The patient's central nervous system abnormalities on MRI and the hemangiomata plana on the ipsilateral upper eyelid and forehead point to Sturge-Weber syndrome. We conclude that the patient has an overlap syndrome between Klippel-Trenaunay syndrome and Sturge-Weber syndrome.
Authors:
Helene Verhelst; Rudy Van Coster
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of child neurology     Volume:  20     ISSN:  0883-0738     ISO Abbreviation:  J. Child Neurol.     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2006-01-18     Completed Date:  2006-02-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  911-3     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Division of Pediatric Neurology, Ghent University Hospital, Belgium. helene.verhelst@ugent.be
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MeSH Terms
Descriptor/Qualifier:
Child, Preschool
Consanguinity
Functional Laterality
Humans
Klippel-Trenaunay-Weber Syndrome / complications*,  radiography*
Magnetic Resonance Imaging
Male
Occipital Lobe / pathology*
Sturge-Weber Syndrome / complications*,  radiography*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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