Document Detail

Neuropsychological sequelae of diffuse traumatic brain injury.
MedLine Citation:
PMID:  15841754     Owner:  NLM     Status:  MEDLINE    
PRIMARY OBJECTIVES: Description and analysis of neuropsychological deficits following brain trauma with diffuse lesion probably corresponding to diffuse axonal injury (DAI).
RESEARCH DESIGN: A series of 111 patients suffering from traumatic brain injury could be investigated neuropsychologically within the first 4 weeks after injury and re-assessed after 5-8 months. They included 11 subjects with CT-evidence of diffuse axonal injury, but no CT-signs of focal contusions. Eleven patients with focal frontal contusions but no CT signs of DAI were matched to and compared with the DAI subjects. Seventeen TBI patients with normal CT scans served as controls.
RESULTS: When assessed within the first 4 weeks after TBI, both DAI and frontal contusion patients exhibited behavioural abnormalities and deficits in Wechsler Similarities. The DAI patients were also impaired in Digit Span backward and Stroop interference. When re-assessed, the DAI patients showed considerable deficits in the California Verbal Learning Test and in the Wisconsin Card Sorting Test.
CONCLUSIONS: DAI leads to neuropsychological impairment dominated by executive and memory dysfunction.
Maike Fork; Claudius Bartels; Anne D Ebert; Claudia Grubich; Hans Synowitz; Claus-W Wallesch
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Brain injury     Volume:  19     ISSN:  0269-9052     ISO Abbreviation:  Brain Inj     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-04-21     Completed Date:  2005-07-12     Revised Date:  2014-11-14    
Medline Journal Info:
Nlm Unique ID:  8710358     Medline TA:  Brain Inj     Country:  England    
Other Details:
Languages:  eng     Pagination:  101-8     Citation Subset:  IM    
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MeSH Terms
Axons / radiography
Brain Injuries / complications,  psychology*,  radiography
Cognition Disorders / etiology,  psychology
Memory Disorders / etiology,  psychology
Mental Disorders / etiology,  psychology
Middle Aged
Neuropsychological Tests
Reaction Time
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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