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Neuropsychological impairment in early-onset hydrocephalus and epilepsy with continuous spike-waves during slow-wave sleep: A case report and literature review.
MedLine Citation:
PMID:  24082936     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Epilepsy with continuous spike-waves during slow-wave sleep (CSWS) is often characterized by a severe cognitive and behavioral impairment. Symptomatic cases also include patients with an early-onset hydrocephalus, but in literature detailed neuropsychological data on these subjects are not available. We describe the results of serial cognitive assessments in a girl with shunted early-onset hydrocephalus, followed by partial epilepsy complicated with CSWS at 4 years 10 months, in which a dramatic cognitive and behavioral deterioration occurred few months after CSWS onset. Adrenocorticotropic hormone treatment improved both clinical and electroencephalogram picture, but an impairment of visual perception, visual-motor coordination and executive functions persisted after CSWS disappearance. We hypothesize, in this case, an involvement of right occipital-parietal lobe and prefrontal lobe.
Annio Posar; Antonia Parmeggiani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric neurosciences     Volume:  8     ISSN:  1817-1745     ISO Abbreviation:  J Pediatr Neurosci     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-10-01     Completed Date:  2013-10-01     Revised Date:  2013-10-17    
Medline Journal Info:
Nlm Unique ID:  101273794     Medline TA:  J Pediatr Neurosci     Country:  India    
Other Details:
Languages:  eng     Pagination:  141-5     Citation Subset:  -    
Child Neurology and Psychiatry Unit, IRCCS Institute of Neurological Sciences of Bologna, Bologna Italy ; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
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