Document Detail

Neuropsychological functioning in children and adolescents with restrictive-type anorexia nervosa: An in-depth investigation with NEPSY-II.
MedLine Citation:
PMID:  23351019     Owner:  NLM     Status:  Publisher    
Several studies have investigated the neuropsychological functioning of patients with anorexia nervosa restrictive type (AN-r), but results are conflicting. Here we compared the neuropsychological profile of 23 female children and adolescents with AN-r and of 46 typical controls (aged 9-16 years) using the second edition of the NEPSY (a Developmental Neuropsychology Assessment) neuropsychological battery. AN-r patients presented subtle cognitive flexibility impairments in audiomotor responses (p = .033). Conversely, superior performance in verbal fluency (p = .024) and memory (p = .034) was observed only in AN-r patients with an associated unipolar mood disorder. This profile of marginally impaired and enhanced performance was independent from illness duration and starvation degree, suggesting that it may preexist and represent a vulnerability factor for the disease onset. This study was supported by the Italian Ministry of Health (C.U., Grant GR-2008-1137139), by IRCCS E. Medea (C.U., Ricerca Corrente 2011, Italian Ministry of Health), and by IRCCS Stella Maris Foundation (F.M., Ricerca Corrente 2011, Italian Ministry of Health). The authors declare that the funding institutions did not influence the study and that no conflict of interest exists.
Sara Calderoni; Filippo Muratori; Chiara Leggero; Antonio Narzisi; Fabio Apicella; Umberto Balottin; Tiziana Carigi; Sandra Maestro; Franco Fabbro; Cosimo Urgesi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-28
Journal Detail:
Title:  Journal of clinical and experimental neuropsychology     Volume:  -     ISSN:  1744-411X     ISO Abbreviation:  J Clin Exp Neuropsychol     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8502170     Medline TA:  J Clin Exp Neuropsychol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
a Istituto di Ricovero e Cura a Carattere Scientifico Fondazione Stella Maris , Pisa , Italy.
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