| Neuropsychological dysfunction after minimally invasive direct coronary artery bypass grafting. | |
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MedLine Citation:
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PMID: 9875760 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: We compared postoperative neuropsychological dysfunction after minimally invasive direct coronary artery bypass grafting (MIDCAB) operation with coronary artery bypass graft operations using cardiopulmonary bypass. METHODS: Neuropsychological assessment was performed preoperatively and before discharge on 7 patients undergoing MIDCAB procedures, 9 patients undergoing single-graft cardiopulmonary bypass operation, and 27 patients undergoing multiple-graft cardiopulmonary bypass operation. From a matched control group of 40 normal subjects reliable change indices were derived for each measure and used to determine the incidence of postoperative decline. RESULTS: There was little difference between the MIDCAB and single-graft cardiopulmonary bypass groups on the incidence of neuropsychologic decline. However, the multiple-graft cardiopulmonary bypass group had a significantly higher incidence of decline than the MIDCAB and single-graft cardiopulmonary bypass groups on specific neuropsychologic measures, coupled with a significantly greater number of postoperative deteriorations per patient. CONCLUSIONS: The elimination of cardiopulmonary bypass does not prevent neuropsychological dysfunction after cardiac operation as patients undergoing MIDCAB and single-graft cardiopulmonary bypass experience similar deteriorations in performance. However, the deterioration is markedly worsened when the number of surgical grafts is increased. |
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Authors:
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M J Andrew; R A Baker; A C Kneebone; J L Knight |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 66 ISSN: 0003-4975 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 1998 Nov |
Date Detail:
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Created Date: 1999-02-03 Completed Date: 1999-02-03 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1611-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Surgery, Flinders Medical Centre and Flinders University of South Australia, Adelaide, Australia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cardiopulmonary Bypass Coronary Artery Bypass / methods* Female Humans Male Mental Disorders / etiology* Middle Aged Nervous System Diseases / etiology Neuropsychological Tests Postoperative Complications Surgical Procedures, Minimally Invasive / adverse effects* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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