Document Detail

Neuropsychological dysfunction after minimally invasive direct coronary artery bypass grafting.
MedLine Citation:
PMID:  9875760     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: We compared postoperative neuropsychological dysfunction after minimally invasive direct coronary artery bypass grafting (MIDCAB) operation with coronary artery bypass graft operations using cardiopulmonary bypass. METHODS: Neuropsychological assessment was performed preoperatively and before discharge on 7 patients undergoing MIDCAB procedures, 9 patients undergoing single-graft cardiopulmonary bypass operation, and 27 patients undergoing multiple-graft cardiopulmonary bypass operation. From a matched control group of 40 normal subjects reliable change indices were derived for each measure and used to determine the incidence of postoperative decline. RESULTS: There was little difference between the MIDCAB and single-graft cardiopulmonary bypass groups on the incidence of neuropsychologic decline. However, the multiple-graft cardiopulmonary bypass group had a significantly higher incidence of decline than the MIDCAB and single-graft cardiopulmonary bypass groups on specific neuropsychologic measures, coupled with a significantly greater number of postoperative deteriorations per patient. CONCLUSIONS: The elimination of cardiopulmonary bypass does not prevent neuropsychological dysfunction after cardiac operation as patients undergoing MIDCAB and single-graft cardiopulmonary bypass experience similar deteriorations in performance. However, the deterioration is markedly worsened when the number of surgical grafts is increased.
M J Andrew; R A Baker; A C Kneebone; J L Knight
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  66     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1998 Nov 
Date Detail:
Created Date:  1999-02-03     Completed Date:  1999-02-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1611-7     Citation Subset:  AIM; IM    
Department of Surgery, Flinders Medical Centre and Flinders University of South Australia, Adelaide, Australia.
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MeSH Terms
Cardiopulmonary Bypass
Coronary Artery Bypass / methods*
Mental Disorders / etiology*
Middle Aged
Nervous System Diseases / etiology
Neuropsychological Tests
Postoperative Complications
Surgical Procedures, Minimally Invasive / adverse effects*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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