Document Detail


Neuropsychiatric manifestations in Langerhans' cell histiocytosis disease: a case report and review of the literature.
MedLine Citation:
PMID:  20595698     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The spectrum of the possible manifestations of Langerhans' cell histiocytosis in children is very wide, ranging from a simple rash to major multiorgan disease. There may be hypothalamic and pituitary dysfunction or more global neurological and neuropsychiatric manifestations when the central nervous system is affected. The cerebellum is preferentially affected for yet undetermined reasons. The clinical presentation includes motor dysfunction as well as cognitive, behavioral, and psychiatric expression of the ongoing neurodegeneration. We report a young patient with Langerhans' cell histiocytosis who underwent an unusual course of psychiatric deterioration.
Authors:
Aviva Mimouni-Bloch; Carolina Schneider; Keren Elishkevitz Politi; Osnat Konen; Doron Gothelf; Batia Stark; Isaac Yaniv; Avinoam Shuper
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Journal of child neurology     Volume:  25     ISSN:  1708-8283     ISO Abbreviation:  J. Child Neurol.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-02     Completed Date:  2010-10-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  884-7     Citation Subset:  IM    
Affiliation:
Pediatric Neurology and Developmental Unit, Loewenstein Rehabilitation Hospital, Raanana, Israel. aviva100@bezeqint.net
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MeSH Terms
Descriptor/Qualifier:
Brain / pathology
Brain Diseases / complications*,  pathology,  therapy
Histiocytosis, Langerhans-Cell / complications*,  pathology,  therapy
Humans
Magnetic Resonance Imaging
Male
Mental Disorders / complications*,  pathology,  therapy
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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